Collagen is the most abundant protein in the human body and plays a fundamental role in wound healing. Different collagen types serve distinct functions during the healing process.
Roles of Collagen Types
- Type III Collagen:
- Found in early granulation tissue.
- Provides a temporary framework for cell migration and angiogenesis.
- Type I Collagen:
- Replaces Type III collagen during the maturation phase.
- Provides tensile strength and durability to the healed tissue.
Collagen in Wound Care Products
- Derived Sources: Collagen dressings are often made from bovine, porcine, or human sources. These products are biocompatible and help stimulate fibroblast activity.
- Applications:
- Hydrolyzed Collagen: Enhances cell proliferation and supports ECM formation.
- Collagen Matrices: Serve as scaffolds for new tissue growth and reduce wound contraction.
Impact on Healing
Collagen-based products accelerate healing by promoting granulation tissue formation, reducing inflammation, and providing a structural framework for cells to repair the wound.
